Hepatic microsomal glucose transport.

نویسنده

  • A Burchell
چکیده

1 Turk, E., Zabel, B., Mundlos, S., Dyer, J. and Wright, E. M. (1991) Nature (London) 350, 354-356 2 Hopfer, U. (1987) in Physiology of Gastro-Intestinal Tract (Johnson, L. R., eds.), 2nd edn., pp. 14991526, Raven Press, New York, NY 3 Semenza, G., Kessler, M., Hosang, M. and Schmidt, U. (1984) Biochim. Biophys. Acta 779,343-379 4 Wright, E. M., Hirayama, B., Hazama, A., Loo, D. D. F., Supplisson, S., Turk, E. and Hager, K. H. (1993) in Molecular Biology and Function of Carrier Proteins, pp. 230-241, The Rockefeller University Press, New York 5 Wood, I. S., Scott, D., Heechey, R. B. and ShiraziBeechey, S. P. (1994) Biochem. SOC. Trans., in the press 6 Lescale-Matys, I,., Dyer, J., Scott, D., Freeman, T. C., Wright, E. M. and Shirazi-Reechey, S. P. (1993) Biochem. J. 291,435-440 7 Hirayama, H. A,, Wong, H. C., Smith, C. D., Hagenbuch, B. A,, Hediger, M. A. and Wright, E. M. (1991) Am. J. I’hysiol. 261, C296-C304 8 Pajor, A. M., Hirayama, B. A. and Wright, E. M. (1992) Am. J. Physiol. 263, R489-K495 9 Vazquex, C. M., Wood, I. S., Dyer, J., Planas, J. M., Ilundain, A. and Shirazi-Beechey, S. P. (1993) Biochem. SOC. Trans. 21,4798 10 Ferraris, R. P. and Diamond, J. M. (1989) Annu. Rev. Physiol. 51, 125-141 11 Farraris, R. P., Villenas, S. A., Hirayama, B. A. and Lliamond, J. (1 992) Am. J. Physiol. 262, 10601068 12 Shirazi-Beechey, S. P., Hirayama, B. A., Wang, Y., Scott, D., Smith, M. W. and Wright, E. M. (1991) J. Physiol. (London) 437,699-708 13 Freeman, T. C., Wood, I. S., Sirinathsinghji, D. J. S., Beechey, R. B., Dyer, J. and Shirazi-Beechey, S. P. (1993) Biochim. Biophys. Acta 1146,203-212 14 Shirazi-Beechey, S. P., Smith, M. W., Wang, Y. and James, P. S. ( 1 99 1 ) J. Physiol. (London) 437, 69 1-698 15 Dyer, J., Scott, D., Reechey, R. B., Care, A. D., Abbas, K. S. and Shirazi-Beechey, S. P. (1994) in Mammalian Brush-Border Membrane Proteins, Part I1 (Lentze, M. J., Grand, R. J. and Naim, H. Y., eds.), pp. 65-72, Thieme Verlag, Stuttgart and New York 16 Scharrer, E., Liebich, H.-G., Raab, W. and Promberger, N. (1979) Zentralbl. Veterinaermed. Reihe A 26,95-105 17 Shirazi-Beechey, S. P., Kemp, R. B., Dyer, J. and Beechey, R. B. (1989) Comp. Riochem. Physiol. B: Comp. Biochem. 94,80 1-806 18 Bassett, J. M. (1975) in Digestion and Metabolism in Ruminants (McDonald, I. W. and Warner, A. C. I., eds.), pp. 383-398, University of New England Publishing Unit, Armidale 19 Shirazi, S. P., Beechey, R. B. and Butterwoth, P. J. (1981) Biochem. J. 194,803-809 20 Shirazi-Reechey, S. P., Gorvel, J.-P. and Heechey, R. B. (1988) J. Bioenerg. Biomembr. 20,273-288 21 Attaix, D. and Mesh, J.-C. (1991) Am. J. Physiol. 261, R811-R818 22 Gordon, J. I. ( 1 989) J. Cell Biol. 10, 1 1871 194 23 Shirazi-Beechey, S. P., Davies, A. G., Tebbutt, K., Dyer, J., Ellis, A,, Taylor, C. J., Fairclough, P. and Beechey, R. B. (1990) Gastroenterology 98,676-685 24 Brown, P. D. and Sepulveda, F. V. (1985) J. Physiol. (London) 363,257-270 25 Flint, N., Cove, F. I,. and Evans, G. S. (1991) Biochem. J. 280,331-334 26 Meddings, J. B., Desouza, Ll., Goel, M. and Thiesen, S. (1990) J. Clin. Invest. 85, 1099-1 107 27 Kinter, W. H. and Wilson, T. H. (1965) J. Cell Hiol. 25, 19-39

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 22 3  شماره 

صفحات  -

تاریخ انتشار 1994